The first 24–48 hours are extremely critical, especially for inhalation anthrax, because early antibiotics can stop toxin production before irreversible damage occurs. With prompt treatment, survival for cutaneous anthrax exceeds 95–99%, while inhalation anthrax survival improves to about 55–75%, compared to historical rates. If treatment is delayed, cutaneous anthrax mortality can rise to 10–20%, and inhalation anthrax becomes far more deadly, with survival dropping to 10–20% or lower, as toxins rapidly cause respiratory failure, sepsis, and shock even after antibiotics are started.