Yes, adults who never had the illness during childhood are still susceptible to it. In fact, the risk of infection remains because immunity is usually acquired only through prior exposure, either from having the illness naturally or through vaccination if available. When adults contract it, the disease often manifests differently compared to children. While the classic symptoms—fever, rash, and subsequent peeling of the skin on fingertips and toes—still appear, adults generally experience more intense systemic effects. Fever may be higher and last longer, fatigue is often more pronounced, and joint pain or body aches can be more severe. Adults also have a higher likelihood of complications, such as secondary bacterial infections of the skin, inflammation of internal organs, or more significant discomfort during the peeling phase. Although the skin changes themselves are similar, the overall course of the illness tends to be tougher on adults, making supportive care and monitoring more important.