The main treatment for cholera is rapid rehydration, which replaces the fluids and electrolytes lost through diarrhea. Oral rehydration solution (ORS) is the first and most effective therapy—it can save over 90% of lives when started early, even without hospital care. For patients who are severely dehydrated or unable to drink, intravenous (IV) fluids are used to restore fluid balance quickly. Antibiotics such as doxycycline or azithromycin are recommended only for severe cases, as they shorten illness duration and reduce bacterial shedding. Mild cases usually recover with ORS alone. Overall, timely rehydration—especially with ORS—is the most crucial and life-saving treatment for cholera.