Yes — the rabies post-exposure vaccine schedule follows a strict timeline to ensure full protection. For people who have never been vaccinated before, the typical regimen is four doses given on days 0, 3, 7, and 14, with day 0 being the day of the first shot. In addition, rabies immunoglobulin (RIG) is given at the same time as the first dose to provide immediate antibodies. For those previously vaccinated, only two booster doses are needed on days 0 and 3, and no immunoglobulin is required. Starting treatment as soon as possible after exposure is crucial.