After a Yellow Fever–infected mosquito bite, symptoms usually appear after an incubation period of about 3–6 days and start suddenly with fever, chills, severe headache, back and muscle pain, fatigue, nausea, and vomiting; early on it can look very similar to malaria or dengue, but clues suggesting Yellow Fever include recent travel to an endemic area, lack of vaccination, prominent back pain, early liver involvement, and later jaundice, while definitive distinction is not possible on symptoms alone, so blood tests and travel history are essential to correctly identify it in the early phase.