For an uninsured traveler, Yellow Fever treatment costs can vary widely by country and severity: a mild to moderate case needing a few days of hospital observation, IV fluids, and tests may cost USD 500 to 3,000 in many low- or middle-income countries and USD 5,000 to 15,000+ in private hospitals or high-income regions, while a severe case requiring ICU care, ventilator support, dialysis, blood products, and longer hospitalization can quickly rise to USD 20,000 to 50,000+, and in countries like the US or parts of Europe, costs may exceed USD 100,000, which is why vaccination and adequate travel insurance are strongly advised.