Treatment costs for Yellow Fever vary widely by country and healthcare quality. In regions like Africa or South America, a mild case requiring a few days of hospitalization can cost around $500–$2,000, while severe cases needing intensive care can exceed $5,000–$15,000 or more in private hospitals. In developed countries or for medical evacuation, costs can skyrocket beyond $20,000–$50,000. Because treatment can be expensive and unpredictable, having travel insurance or receiving vaccination beforehand is strongly advised.