While the Yellow Fever vaccine is generally safe and highly effective, it is not suitable for everyone due to the risks associated with its live virus. It should not be given to infants under 9 months of age, as their immune systems may not handle the vaccine properly. Additionally, people with weakened immune systems, such as those undergoing chemotherapy, organ transplant recipients, or individuals with HIV/AIDS, should avoid the vaccine. Pregnant women and those who are breastfeeding should also refrain from receiving the vaccine unless traveling to a Yellow Fever-endemic area and there is no alternative. People with a severe allergy to eggs or gelatin, both of which are used in the vaccine production, should avoid it. Moreover, individuals with certain thymus disorders (like thymoma or those who have had a thymectomy) should not be vaccinated. If you fall into any of these groups, it’s essential to speak with a healthcare provider to assess the risks and explore other preventive measures.